Table 1.
Variegated expression of lentigenes transmitted by females (F) versus males (M)
| Lines | Generation | Parent sex and % GFP+* |
Offspring % GFP+* |
|---|---|---|---|
| KD7–26 | F0 | 33 | |
| F1 | F, 33 | 0, 18; 0 | |
| F2 | M, 18 | 64, 68, 73, 76 | |
| F3 | F, 76 | 10, 1, 36, 33, 15 | |
| M, 64 | 90, 89, 81, 95; 96, 96, 93 | ||
| F4 | F, 81 | 30, 72, 42, 20 | |
| M, 90 | 99, 95 | ||
| KD7–20 | F0 | 31 | |
| F1 | M, 31 | 97, 1, 2, 96, 97, 98; 0, 96 | |
| F2 | M, 98 | 94, 96 | |
| M, 96 | 91, 91, 92; 97, 96 | ||
| F3 | M, ND | 96, 98, 97, 100 |
Litters by the same parent were separated with a semicolon. ND, not determined.
*GFP marker expression was monitored in each generation of lentigenic mice by flow-cytometric analysis of peripheral blood mononuclear cells. The numbers are percentages of GFP+ cells in the CD4+ subset of individual animals. Patterns also reflect CD8+ cells.