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Comparison of the accumulation of p21WAF1/CIP1 (A) and gelsolin (B) in various human tumor lines exposed to MS-27-275. Lysates (45 μg of total protein) from the cells exposed to 0.3 μM MS-27-275 for 0, 24, 48, and 72 h were analyzed by Western blotting by using specific antibodies to p21WAF1/CIP1 and gelsolin as described in Materials and Methods.
