TABLE 1.
Effects of IFN-α and cell type on viral yield
| Virus strain | Gene inactivated | −IFN/+IFN ratioa for indicated cell group
|
||||
|---|---|---|---|---|---|---|
| PELF | PESF | REF | MEF | HFF | ||
| PRV Becker | None | 2.4 | 2 | 2.3 | 2.9 | — |
| PRV EP0-1 | EP0 | 297 | 114 | 5.6 | 7.1 | — |
| HSV-1 KOS | None | — | — | — | 2.8 | 90 |
| HSV-1 n212 | ICP0 | — | — | — | 2.2 | 58 |
| HSV-1 d99 | ICP0 | — | — | — | 12 | 107 |
a
The ratio was determined by dividing the viral titer obtained from nontreated cells by the titer obtained from pretreated cells. Each titer measurement was an average obtained from three independent experiments. −IFN, nontreated cells; +IFN, pretreated cells; —, not done.