FIG. 2.

Treatment protocol and longitudinal analysis of viral load in SIV-infected sooty mangabey. (a) SMs were assigned to three groups treated with different protocols. Animals were studied for 64 days. At various time points through the study, plasma, peripheral blood, and lymph node were collected. Flu, fludarabine. (b) Temporal trend of viral load at various time points during the study in SIV-infected SMs treated with fludarabine (gray dotted line), PMPA (dark gray dashed line), and fludarabine plus PMPA (black). Viral load is presented as mean ± standard deviation of SIV RNA copies/milliliter of plasma of the two animals included in each group. Numbers in square bracket at day 36 and day 43 represent the fold increase in viral load compared to day 28 (end of treatment) found in group 2 and group 3.