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. 2006 Aug 30;80(21):10683–10691. doi: 10.1128/JVI.01009-06

TABLE 2.

Phenotypes of donor PBMC and proviral loads of cells recovered from infected hu-PBMC-NOG micea

Donor Surface markers of donor PBMC (%)b
Proviral load (%)c
CD3 CD4 CD8 CD19 Lavage specimen Spleen
D 69.7 61.8 18.7 12.2 3.7 0.6
34.0 1.4
2.8 0.5
E 84.7 53.4 33.9 3.0 0.6 0.1
12.6 1.0
11.6 0.8
F 67.0 48.0 31.9 2.8 0.2 0.0
2.7 0.2
0.6 0.1
G 74.9 43.9 37.7 1.3 7.4 0.2
2.8 0.6
H 80.0 62.8 18.0 1.2 2.4 0.2
0.4 0.0
I ND ND ND ND 20.5 2.5
0.1 0.3
a

PBMC from the indicated donors were transferred into NOG mice, and these were sacrificed 2 weeks after inoculation of 104 MMC-treated MT-2 cells.

b

The percentage of cells positive for the specified markers before transfer into mice is shown for each donor.

c

The proviral loads of human cells recovered from peritoneal lavage and spleens of the different mice are shown as percentages, calculated as described in Materials and Methods. ND, not determined.