TABLE 1.

Virus sequence alignments

Virusa	Subset	No. of sequencesb	Length (nt)c	No. of groupsd	Divergencee
					Intergroup	Intragroup
Picornaviridae
FMDV	A-O	103	8,386	4 (S)	0.176	0.105
	SAT	18	8,386	3 (S)	0.220	0.139
Enterovirus	HEV-A	28	7,656	3 (S)	0.301	0.187
	HEV-C	62	7,656	8 (S)	0.277	0.210
	HEV-C	51	7,656		0.334	0.145
Teschovirus		31	7,127	11 (S)	0.212	0.171
Flaviviridae
Flavivirus	JEV group	30	11,117	3 (S)	0.409	0.118
	Dengue virus	83	10,787	4 (S)	0.337	0.065
	YFV	7	10,862	4 (G)	0.218	0.032
	TBE group	12	11,141	3 (S)	0.365	0.138
HCV		127	9,519	6 (G)	0.437	0.189
HGV/GBV-C		37	9,476	4 (G)	0.144	0.113
Pestivirus		44	12,596	4 (G/S)	0.433	0.142
Alphaviridae		47	10,707	4 (S)	0.665	0.146
Caliciviridae	Noroviruses	24	8,071	16 (S)	0.618	0.039
Astroviridae	Human	10	6,882	6 (S)	0.233	0.088

^aA full listing of sequences in each alignment is available from the author.

^bNumber of sequences in alignment.

^cLength of alignment (including alignment gaps).

^dNumber of predefined groups. The classification method is indicated in parentheses. S, serologically defined; G, genotypic classification.

^eMean pair-wise Jukes-Cantor-corrected distance between and within groups of complete genome sequences.