FIG. 4.

Analysis by the conventional assay of chromosomal features associated with WT and NL-Mme virus integration events. CEM cells were infected with WT or NL-Mme virus at an MOI of 10. Integration sites were mapped using the conventional assay, and chromosomal features associated with WT (gray bars) and NL-Mme (black bars) proviruses were analyzed. The results are expressed as percentages of total integration events and compared with those of the random control (open bars). Chromosomal features analyzed include transcription units (TU), Alu and mammalian interspersed repeat (MIR) of the SINE, L1 and L2 of the LINE, LTR-E, and DNA-E.