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. 2006 Aug 30;80(22):11209–11217. doi: 10.1128/JVI.01173-06

FIG. 2.

FIG. 2.

A peptide VP1/2 7.2-specific TCL can respond to stimulation with both peptide VP1/2 7.2 and VP2 recombinant capsid and can be shown to respond in a DRB1*1501-restricted manner. (A) ICS on 17-day-old peptide VP1/2 7.2-specific TCL (from individual OR3) stimulated with peptide VP1/2 7.2. Percentages shown are the numbers of IFN-γ-positive CD4+ T cells. (B) ICS on 17-day-old peptide VP1/2 7.2-specific TCL (from individual OR1) stimulated with peptide VP1/2 7.2 and VP2 recombinant capsid. Percentages shown are the numbers of IFN-γ-positive CD4+ T cells. (C) A peptide VP1/2 7.2-specific TCL from OR1 was rechallenged 17 days later with DRB1*1501-positive L cells (prepulsed with peptide VP1/2 7.2, VP1/2 3.4, or mock peptide) in an ICS assay. Percentages shown are the numbers of IFN-γ-positive CD4+ T cells.