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. 2006 Jun 15;361(1471):1187–1209. doi: 10.1098/rstb.2006.1856

Table 2.

Summary of agonist affinities of Y-family receptor subtypes. (NPY, neuropeptide Y; PP, pancreatic polypeptide; PYY, peptide YY (see also Berglund et al. 2003).)

receptor high-affinity agonists intermediate-affinity agonists low-affinity agonists
Y1 NPY, PYY, Leu31,Pro34NPY/PYY NPY2-36, NPY3-36, NPY13-36 PP
Y2 (presynaptic) NPY, PYY, PYY3-36 Leu31,Pro34NPY/PYY PP
Y4 PP, NPY, PYY, Leu31,Pro34NPY/PYY NPY2-36 NPY/PYY fragments PYY3-36
Y5 NPY, PYY, NPY2-36, NPY3-36, PYY3-36, Leu31,Pro34NPY/PYY PP, NPY13-36, PYY13-36 NPY/PYY fragments
y6 non-functional in man