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. 2003 May 8;100(11):6646–6651. doi: 10.1073/pnas.0631696100

Fig. 3.

Fig. 3.

TOG activates murine macrophages and dendritic cells. (A) TOG activates macrophages. BMDMs from C57BL/6 mice were stimulated for 24 h with TOG (100 μM), pam3Cys (5 μg/ml), p(I:C) (5 μg/ml), LPS (10 ng/ml), R-848 (1 μM), or CpG (5 μg/ml). The production of IL-6 and IL-12(p40) was measured by ELISA. (B) TOG activates dendritic cells. BMDDCs from C57BL/6 mice were stimulated for 24 h with TOG (100 μM), LPS (10 ng/ml), R-848 (1 μM), or CpG (5 μg/ml). The induction of cell surface markers was measured by flow cytometry.