Table 1. CCR2 mRNA in various tissues during chronic pain states.
CFA
|
Nerve injury
|
||||||
---|---|---|---|---|---|---|---|
2 days | 2 days | 4 days | 1 wk | 2 wk | 3 wk | 4 wk | |
Paw skin | 21.1±4.7 | 4.8±0.2 | 2.8±0.2 | 1.5±0.1 | 1.9±0.2 | 0.8±0.1 | 1.0±0.1 |
Sciatic nerve | 2.4±2.4 | 6.6±0.1 | 8.3±0.5 | 3.0±0.7 | 5.0±0.8 | 1.7±0.1 | 3.4±0.4 |
DRG | 2.8±0.4 | 5.4±0.2 | 6.0±0.6 | 4.3±0.5 | 6.3±0.0 | 3.2±0.1 | 5.6±0.5 |
Spinal cord | 0.5±0.1 | 1.4±0.1 | 1.4±0.1 | 1.1±0.7 | 0.5±0.1 | 0.9±0.1 | 0.6±0.1 |
Results are expressed as mean ± SD fold over control