Table 4.

Calculated tunnelling rates for cytochrome oxidase by various groups over time. (Numbers in parenthesis are the λ estimates in eV.)

reaction	measured electron tunnelling rate (s−1)	calculated rate
average protein	pathways based analysis				packing density
Moser et al. (1992) with 1995 structurea	Regan et al. (1998)	Medvedev et al. (2000)	George (2001)	Tan et al. (2004)	this work
CuA→a	2×104b	3×103 (0.7)	2×104 (0.09)	3.3×102 (0.3)	1.3×104 (0.3)	6×104 (0.3)	8.7×104 (0.7)
a→a3 pre-2001	3×105	6.5×108 (0.7)	3×105 (0.44)	5.9×104 (0.76)b
a→a3 post-2001	7×108b					3×108 (0.76)	1.4×109 (0.7)
CuA→a3	4c	90 (0.7)	40 (0.5)	0.17 (0.8)			250 (0.7)

^aIwata et al. (1995).

^bAdelroth et al. (1995).

^cKannt et al. (1999).