TABLE 3.
Genes down-regulated by T0901317
| Gene | Name | Fold changea
|
|
|---|---|---|---|
| +WT/ −WT | +DN2-TG/ +WT | ||
| AA108438 | EST | 0.37 | 0.86 |
| AA239479 | EST | 0.43 | 0.69 |
| W66757 | EST | 0.46 | 1.16 |
| A1604749 | EST | 0.47 | NA |
| AA014384 | EST | 0.47 | 2.01 |
| AA213017 | Monooxygenase 3 | 0.48 | 2.20 |
| AA271451 | C-reactive protein, pretexin related | 0.49 | 1.46 |
| AA285921 | Major urinary protein 2 | 0.50 | 1.00 |
| AA245847 | EST | 0.50 | 1.00 |
| W83009 | EST | 0.50 | 1.08 |
| AA238208 | EST | 0.51 | 1.00 |
| AA154452 | EST | 0.51 | 1.10 |
| AA542013 | Fibroblast growth factor receptor | 0.52 | 0.96 |
| AI385792 | Sulfotransferase-related protein | 0.52 | 0.69 |
| AA218405 | 1KKɛ | 0.52 | 1.00 |
| W11846 | EST | 0.53 | 1.27 |
| AA239480 | EST | 0.54 | 1.13 |
| AA259979 | Angiotensinogen | 0.54 | 1.26 |
| AA213062 | EST | 0.54 | 1.12 |
| W18484 | MEL91 | 0.55 | NA |
| AA260520 | Ets variant gene 6 | 0.56 | 1.09 |
| AA476030 | EST | 0.57 | 0.80 |
| AA212899 | Deiodinase, iodothyronine, type | 0.57 | 0.96 |
| AA277314 | Angiogenin-3 | 0.57 | 1.55 |
| W11759 | EST | 0.57 | NA |
| AA241936 | EST | 0.57 | 0.98 |
| AI893937 | Protein tyrosine phosphatase | 0.58 | 1.00 |
| AA414106 | EST | 0.58 | NA |
| AA153024 | EST | 0.58 | 1.13 |
| AI605748 | EST | 0.59 | 0.93 |
| AA266146 | EST | 0.59 | 1.01 |
| W47974 | EST | 0.59 | NA |
| W34018 | EST | 0.60 | NA |
| AA062129 | Inter-αtrypsin inhibitor, hc 3 | 0.60 | 0.80 |
| AA122791 | Histocompatibility 2, Q locus 7 | 0.60 | 1.15 |
| W10072 | IGF 1 | 0.60 | 0.89 |
| AI390830 | EST | 0.60 | 0.90 |
| AA174320 | EST | 0.60 | 1.77 |
a
+, treated with T0901317; −, treated with vehicle; italics, significantly up-regulated in DN2-TG mice.