FIG. 1.

Comprehensive CTL screening and testing of optimal epitopes. Data for one representative subject (TCH-061) are shown, with responses to previously described optimal epitopes shown on the left and responses to the corresponding overlapping 18mer on the right. Brackets indicate adjacent peptides that overlap. In this subject, only four responses were detected by using previously defined optimal epitopes, whereas each of these plus an additional four responses were detected by comprehensive screening with overlapping peptides.