TABLE 1.

EBV infection with HLA class II mutants

Mutant	Relative infection avga	No. of infections
DQ 2	1 (NA)c	5
R 23 D	0.59 ± 0.11	4
R 25 D	0.71 ± 0.16	3
R 34 E	0.94 ± 0.23	3
E 36 K	0b	3
D 41 A	0.79 ± 0.03	4
D 43 A	0.53 ± 0.05	4
R 48 E	0.72 ± 0.27	5
E 69 K	0.57 ± 0.21	4
S 42 A	1.1 ± 0.20	4
S 42 K	0.8 ± 0.09	4
E 46 K	0.08 ± 0.06	3
S 63 A	0.72 ± 0.20	4
S 63 K	0.57 ± 0.37	3
K 65 A	1.09 ± 0.16	3
K 65 E	0.12 ± 0.10	4
R 72 A	0.26 ± 0.10	4
R 72 E	0.00 ± 0.01	4

^aThis number is equal to the relative infection rate with the standard deviation for each mutant. For each experiment, the percentage of GFP-positive cells was divided by the percentage of HLA-DQ-positive cells in and compared to the ratio for wild-type DQ 2 when it was set at 1.

^bNo surface expression was detected.

^cNA, not applicable.