TABLE 1.
Effect of CAG and CTG repeats of different lengths on APRT activity
| n for APRT(CAG)n | APRT+, %a
|
n for APRT(CTG)n | APRT+, %a
|
||
|---|---|---|---|---|---|
| Transient transfection | Stable integrants | Transient transfection | Stable integrants | ||
| 17 | 91 ± 2 | 98 ± 10 | 17 | 93 ± 5 | 84 ± 10 |
| 25 | 105 ± 10 | NA | 25 | 112 ± 12 | NA |
| 32 | 91 ± 4.5 | NA | 28 | 92 ± 4.6 | NA |
| 67 | 11 ± 11 | NA | 32 | 106 ± 6.5 | NA |
| 98 | 12 ± 10 | <0.1 | 98 | 112 ± 13 | 102 ± 3.4 |
| 175 | 10 ± 11 | <0.1 | 175 | 91 ± 7.5 | 97 ± 9.6 |
a
Percentage of APRT+ clones from the total number of transfectants (APRT+ clones/gpt+ clones) (100). Standard errors are indicated.