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Impaired motility of Nck1−/− Nck2−/− MEFs. Confluent monolayers of Nck1+/− Nck2+/−, Nck1−/− Nck2−/−, and Nck1-rescued MEFs were mechanically interrupted, and the inflicted wounds were photographed at the indicated time points (in hours). Nck1−/− Nck2−/− cells exhibited reduced ability to migrate into the wound compared to Nck1+/− Nck2+/− and Nck1-rescued MEFs.
