(A) Sequence alignment of Sso10b proteins from different archaeal organisms, including Sso10b2 (GenBank accession no. P74762) and Sso10b1 (Q971T6) from Sulfolobus solfataricus, Mka1 from Methanopyrus kandleri (Q8TXF9), Afu1 from Archaeoglobus fulgidus (O28323), Pfu1 from Pyrococcus furiosus (Q8TZV1), Mth from Methanopyrus kandleri (Q8TWE6), Ape from Aeropyrum pernix (Q9YAX2), Mja from Methanococcus jannaschii (Q57665), Pae from Pyrobaculum aerophilum (Q8ZVL3), and Tvo from Thermoplasma volcanium (Q979S5), are aligned. Orange, yellow, and light blue indicate the level of homology (100, 70, and 50%, respectively) of these genes. The secondary structures of Sso10b2 and Sso10b1 are shown below the alignment. (B) Carton presenting the βαβαββ topology of Sso10b2.