TABLE 1.
Regions of the TLR-5 sequence for which a complementary hydropathy with the flagellins of three bacterial species was founda
| TLR-5 | Flagellinb
|
||
|---|---|---|---|
| I | II | III | |
| LLERLQLLEL | ERLASGKRIN | ||
| LRILDLGQSQ | NLQRVRELAV | ||
| RILDLGQSQI | LQRVRELAVQ | LQRIRDLALQ | |
| IEVLNRDAFQ | RVRELAVQSA | RIRDLALQSA | |
| FNQIFTICED | NILQRIRDLA | ||
| NQIFTICEDE | ILQRMRQLAV | ILQRIRDLAL | |
| QIFTICEDEL | LQRVRELAVQ | LQRIRDLALQ | |
| RGVRLETLDL | LINIDLFNAK | ||
| VDLQRNHIGI | KIDAALAQVD | ||
| KLVHLPHIHF | VKNVQVANAD | ||
| IHFTANFLEL | EINNNLQRVR | ||
| NFLELSENRL | LQRVRELAVQ | LQRIRDLALQ | |
| LYFLLRVPQL | EINNNLQRVR | ||
| LPANLEILDI | TIDIDLKQIN | ||
| LEILDISRNQ | NLQRVRELAV | ||
| EILDISRNQL | LQRVRELAVQ | LQRMRQLAVQ | LQRIRDLALQ |
| EILDISRNQL | LQKIDAALAQ | ||
| ILDISRNQLL | QRVRELAVQS | QRIRDLALQS | |
| LRVLDITHNE | NLQRVRELAV | ||
| RVLDITHNEF | LQRVRELAVQ | LQRIRDLALQ | |
| LFLVITLVVI | KTQEYLRKNN | ||
| LVVIKFRGIC | NYNNIKLLDQ | ||
a
A complementary region common to the three flagellins is shown in bold.
b
I, S. enterica serovar Typhimurium; II, L. monocytogenes; III, P. aeruginosa.