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. 2003 Jan 20;5(2):R106–R113. doi: 10.1186/ar624

Figure 2.

Figure 2

The number of CD4+CD25+-expressing regulatory T cells from BALB/c and C57BL/6 mice during immunization. (a) BALB/c and C57BL/6 mice, immunized with proteoglycan (PG) or ovalbumin (OVA), were killed at 14 days after each immunization, and levels of expression of the CD4+CD25+ T cells were determined by flow cytometry. *The CD4+CD25+ T cells from naïve BALB/c and C57BL/6 mice were also determined. (b) Cytotoxic T-lymphocyte antigen (CTLA)-4 expression on the CD4+CD25+ T cells from PG- or OVA-immunized animals (after the 3rd injection) was determined.