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. 2003 Apr 29;5(4):R193–R201. doi: 10.1186/ar756

Table 3.

Expression of HIF-1α and HIF-2α in normal, rheumatoid, and osteoarthritic synovium

Fractures RA OA P
HIF-1α
 Negative 16 0 0
 Low 6 10 13 <0.0001
 High 0 12 21
HIF-2α
 Negative 18 0 0
 Low 4 8 14 <0.0001
 High 0 14 20

HIF, hypoxia inducible factor; OA, osteoarthritis; RA, rheumatoid arthritis.