Table 1.
Cell type | MESF (in thousands) Baseline expressiona | Range |
Lymphocyte | 9.5 (1.2) | 4.45–14.17 |
Monocyte | 35.4 (3.3)* | 13.90–44.32 |
Neutrophil | 13.8 (3.3) | 9.14–18.28 |
Intracellular TTP levels were detected using the TTP antibody in conjunction with a fluorescein-labelled antirabbit Ig. Background levels were subtracted from these results and CD14-staining plus forward and side scatter gating permitted specific analysis of TTP expression in the leukocyte populations. Monocytes have a significantly higher constitutive TTP expression than other leukocytes. aMean (SE); n = 8. *P < 0.001. MESF = milliequivalents of soluble fluorescein.