Table 2.

Expression in vivo of tristetraprolin in volunteers

Volunteer no.		Neutrophils	Lymphocytes	Monocytes
1	Baseline	16.5 (1.2)	18.8 (1.0)	15.6 (1.6)
	Peak	54.9 (2.0)	90.4 (8.8)	18.9 (2.4)
2	Baseline	15.6 (1.2)	9.9 (1.0)	23.2 (2.0)
	Peak	17.1 (3.6)	13.1 (1.2)	40.8 (4.3)
3	Baseline	9.7 (8.2)	4.2 (0.5)	20.8 (1.3)
	Peak	20.8 (1.4)	9.4 (2.3)	62.0 (29.0)
4	Baseline	13.6 (1.1)	6.0 (0.6)	16.6 (1.7)
	Peak	17.5 (1.1)	19.1 (1.8)	47.2 (1.6)

Values are mean milliequivalents of soluble fluorescein (SE) (in thousands). Human subjects were infused with a bolus dose of lipopolysaccharide at T = 0. Blood was drawn at specific times before and after infusion, and the leukocytes were purified by dextran sedimentation. Expression of tristetraprolin was determined by flow cytometry.