Figure 4.

Stereo view illustrating local symmetry within a 1/12th subunit. The density corresponding to the dodecameric hemoglobin complex is shown in magenta, the density corresponding to both the long and short triple-stranded coiled-coils is shown in yellow, and the remainder of the linker density is depicted in blue. The approximate local threefold that relates the hemoglobin subunits and the globular portion of the linker complex is vertical. Note the sharp break in symmetry axis between the short and long coiled-coils.