Table 1.
X-box sequence in the promoter region of xbx-1 and its putative orthologs
Species | Locationa | X-box Sequenceb | |
---|---|---|---|
C. elegans | -79 to -66 ATG | G T T T C C AT | G G T A A C |
C. briggsae | -93 to -80 ATG | G T T T C C AT | G G T T A C |
Drosophila | -68 to -54 ATG | G T T G C T AGT | A G C A A C |
Human | -67 to -54 ATG | G C T C C C AT | G G C A A C |
Consensus X-box | G T N R C C N (0-3) | R G Y A A C |
Note: The sequence of the five prime end of the mouse ortholog has not yet been completed and thus the presence of an X-box could not be evaluated.
ATG denotes translational start site.
R = G/A; Y = C/T; N = G/A/T/C; bold denotes a match to the mammalian X-box consensus sequence (Emery et al., 1996).