Figure 7.

Influence of recombinant laminin LG modules on laminin-10/11 mediated ERK activation. WI-26 VA4 cells were pretreated with the indicated LG modules as described in Figure 6. The cells were then allowed to attach on laminin-10/11 for 1 h in the presence or absence of the indicated LG modules. The presence of ERK1 and phosphorylated pERK1/2 is indicated and quantitative measurements of the phosphorylation status are shown in the lower panels. Two of the three experiments with similar results are shown.