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(a) Schematic diagram illustrating the domain organization of the four NFAT family members. The regulatory domain comprises the NFAT-h and the sequences N terminal to it. DBD, DNA binding domain. (b) CD spectra of NFAT in the unphosphorylated and phosphorylated forms. (Inset) SDS/PAGE gel showing the shift in electrophoretic mobility of NFAT1–414 caused by phosphorylation.
