FIG. 1.

Schematic presentation of the l-arabinose utilization pathway engineered in S. cerevisiae. l-Arabinose is transported into the cell by the galactose permease Gal2 and subsequently converted to d-xylulose-5-P by three enzymatic steps. d-Xylulose-5-P is an intermediate of the pentose phosphate pathway and is directed to glycolysis by transketolase (TKL) and transaldolase (TAL). ZWF, glucose-6-P dehydrogenase; PGL, phosphogluconolactonase; GND, gluconate-6-P dehydrogenase; RPI, ribose-5-P isomerase; RPE, ribulose-5-P 3-epimerase.