FIG. 2.
Multiple-sequence alignment of TPMTs. The sequence of bTPMT of Pseudomonas sp. strain Hsa.28 (accession no. AY259120) (P. Has.28) and TPMT sequences available in databases were aligned by using Clustalw. The SeqVu program (version 1.0.1; Garvan Institute of Medical Research, Darlinghurst, Sydney, Australia) was used to visualize identical residues (shaded residues in boxes) and similar residues (shaded residues). The following sequences were included: B.pertussis, deduced protein from B. pertussis vrg-18 promoter region (accession no. M37228); Hsa-liver, human liver TPMT (accession no. P51580); Hsa-lymph, human lymphocyte TPMT (accession no. U11424); P. syringae, P. syringae pathovar pisi TPMT (accession no. L49178); Synechocystis, Synechocystis putative methyltransferase (accession no. D64003); V. cholerae, putative V. cholerae TPMT (accession no. NP_230871); P. aeruginosa, putative P. aeruginosa TPMT (accession no. NP_251522); P. stutzeri, partial putative P. stutzeri TPMT (accession no. CAC44176).