FIG. 2.
Identification of a potential GalR binding site upstream of aga. (A) Alignment of the putative GalR binding site from L. raffinolactis and S. thermophilus (34) with the DNA sequence protected by GalR from DNase I digestion in S. mutans (1). The −10 and −35 boxes are indicated in bold. For L. raffinolactis, only the −10 box is provided. The transcription start nucleotide is boxed in black, and the ATG start codon is underlined. (B) Alignment of the N termini of S. thermophilus (S. t.), S. mutans (S. m.), and L. raffinolactis (L. r.) GalR proteins. The helix-turn-helix motif is in bold. |, identical positions; +, conservative substitutions.