TABLE 3.
Classification and putative functional domains of HPKs and RRs identified in this study
| ORF | Size (amino acids) | Positiona (amino acids) or homology
|
Class or group | |||
|---|---|---|---|---|---|---|
| N-terminal domainsa
|
C-terminal domain HATPase-c or effector | |||||
| Transmembrane or receiver | HAMP | HPK-A | ||||
| BikA | 565 | 29-51 | 210-278 | 290-356 | 402-513 | IIIA |
| 172-194 | ||||||
| 207-229 | ||||||
| BikB | 448 | 51-73 | 69-121 | 134-202 | 266-413 | IIIA |
| BikC | 348 | N/A | N/A | 172-241 | 275-321 | II |
| BirA | 240 | CheY | PhoP/OmpR | 2 | ||
| BirB | 227 | CheY | OmpR/PhoB | 2 | ||
| BirC | 214 | CheY | NarL/DegU | 3 | ||
a
HAMP, histidine kinase, adenlyl cyclase, methyl binding protein, phosphatase domain; HPK-A, histidine kinase A motif; HATPase-c, histidine kinase-, DNA gyrase B-, phytochrome-like ATPase. N/A, not apparent.