TABLE 4.

2CSs identified in B. infantis UCC35624 and their surrounding ORFsa^a

ORF	Size (amino acids)	ORF with highest similarity score	Organism	Identity (%)	P	GenBank accession no.
System A
GtpA	459	Hypothetical protein	B. longum DJO10A	96	0.0	ZP_00121667
BirA	240	Hypothetical protein	B. longum DJO10A	80	1e-101	ZP_00121666
BikA	565	Hypothetical protein	B. longum DJO10A	96	0.0	ZP_00121665
LipA	467	Hypothetical protein	B. longum NCC2705	93	0.0	NP_695263
BiaA	324	Probable solute-binding protein of ABC transporter system, possibly for sugars	B. longum NCC2705	93	1e-149	NP_695264
BiaB	504	ATP-binding protein of ABC transporter	B. longum NCC2705	100	0.0	NP_695265
BiaC	696	Hypothetical protein	B. longum DJO10A	88	1e-138	ZP_00121659
System B
BirB	227	Hypothetical protein	B. longum DJO10A	91	2e-91	ZP_00121583
BikB	448	Histidine kinase sensor of two-component system	B. longum NCC2705	96	0.0	NP_695237
System C
BikC	348	Sensor histidine kinase	Pseudomonas syringae pv. tomato DC3000	42	1e-20	NP_791953
BirC	219	Putative two-component system regulator	Streptomyces coelicolor A3(2)	40	2e-17	NP_627834

^aSee also Fig. 2.