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Effect of oseltamivir carboxylate on the formation of virus foci in parallel cultures of MDCK (M) and MDCK-SIAT1 cells (ST) infected with the same virus multiplicity. Experiments were performed in 96-well plates as described in Materials and Methods using clinical virus isolates A/Sydney/5/97 (H3N2) (top panel), A/Memphis/14/96-M (H1N1) (middle panel), and B/Memphis/25/99 (bottom panel). The infection time was 24 h for the type A viruses and 48 h for the type B virus.
