TABLE 3.
Neurovirulence of Qalyubiya/88-1 and Beni Suef/93 in PVR-Tg21 transgenic mice
| Isolate | No. of mice killed/total no. inoculated with a dose (TCID50/mouse) of:
|
PD50b | ||||||
|---|---|---|---|---|---|---|---|---|
| 7.5 | 6.5 | 5.5 | 4.5 | 3.5 | 2.5 | 1.5 | ||
| Qalyubiya/88-1 | —a | — | — | — | 5/6 | 3/6 | 1/6 | 2.5 |
| Beni Suef/93 | — | — | — | — | 6/6 | 2/6 | 0/6 | 2.7 |
| MEF-1/EGY42 | — | — | — | — | 6/6 | 3/6 | 0/6 | 2.5 |
| Sabin 2 | 0/6 | — | — | — | — | — | — | >8.0 |
a
—, not done.
b
Values represent the virus titer that induced paralysis or death in 50% of inoculated mice (PD50) and are expressed as a multiple of the TCID50.