TABLE 1.
Virion infectivitya of wt and DIS mutant HIV-1
| Cells | TCID50 (10−3 cpm) of RT activity in experiment no.:
|
|||||||
|---|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | |
| PBMCs | ||||||||
| NL4.3 | 150,000 | 3,200 | 560,000 | 320,000 | 320 | 560 | 320,000 | 56,000 |
| NLACGCGT | 320,000 | 560 | 32,000 | 180,000 | 180 | 56 | 32,000 | 5,600 |
| NLGCGCGC | 5,600 | 56 | 32,000 | 320,000 | 32 | 56 | 460,000 | 32,000 |
| SupT1 | ||||||||
| NL4.3 | 32,000 | 3,200 | 3,200 | 1,800 | 180,000 | 320,000 | ||
| NLACGCGT | 3.2 | 0.56 | 0.56 | 3.2 | 3.2 | 0.32 | ||
| NLGCGCGC | 3.2 | 3.2 | 0.56 | 3.2 | 5.6 | 0.56 | ||
a
TCID50 was measured as described in Materials and Methods. cpm, counts per minute.