TABLE 1.

Comparison of the HIV-1 NC Zn²⁺ fingers with the seven Zn²⁺ fingers from human CNBP

Zn2+ finger	Amino acida at position:
	1	2	3	4	5	6	7	8	9	10	11	12	13	14
HIV-1 NH2 terminus	Cys	Phe	Asn	Cys	Gly	Lys	Glu	Gly	His	Ile	Ala	Lys	Asn	Cys
CNBP-1b	-	-	Lys	-	-	Arg	Ser	-	-	Trp	-	Arg	Glu	-
CNBP-2	-	Tyr	Arg	-	-	Glu	Ser	-	-	Leu	-	-	Asp	-
CNBP-3	-	Tyr	-	-	-	Arg	Gly	-	-	-	-	-	Asp	-
CNBP-4	-	Tyr	-	-	-	-	Pro	-	-	Leu	-	Arg	Asp	-
CNBP-5	-	Tyr	Ser	-	-	Glu	Phe	-	-	-	Gln	-	Asp	-
CNBP-6	-	Tyr	Arg	-	-	Glu	Thr	-	-	Val	-	Ile	-	-
CNBP-7	-	Tyr	Arg	-	-	Glu	Ser	-	-	Leu	-	Arg	Glu	-
HIV-1 COOH terminus	-	Trp	Lys	-	-	-	-	-	-	Gln	Met	-	Asp	-

^aThe positions of the first amino acids of the HIV-1 NH₂- and COOH-terminal NC Zn²⁺ fingers are 15 and 36, respectively. The positions of the first Cys residue in each of the seven human CNBP Zn²⁺ fingers are 6, 54, 74, 97, 119, 137, and 158 (45). A dash (-) indicates that the amino acid is the same as that found in the HIV-1 NH₂-terminal NC Zn²⁺ finger.

^bThe number after CNBP refers to the order of the Zn²⁺ finger from the NH₂ terminus out of a total of seven Zn²⁺ fingers.