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TABLE 2.

Acute-phase and set point viral burdens in immunized and control macaques

Macaques Acute-phase burdenb
Set point burdenb
Immunized Control P value Immunized Control P value
All immunized versus all control 2.38 × 106 3.28 × 107 <0.0001 5.56 × 105 1.65 × 106 0.21
Non-Mamu-A∗01 only
    Immunized versus control 2.64 × 106 4.66 × 107 0.0001 8.76 × 105 3.48 × 106 0.18
    Immunized-low burdena versus control 3.43 × 106 4.66 × 107 <0.01 7.20 × 104 3.48 × 106 <0.01
    Immunized-intermediate burdena versus control 1.75 × 106 4.66 × 107 <0.01 1.23 × 106 3.48 × 106 <0.01
    Immunized-high burdena versus control 3.06 × 106 4.66 × 107 <0.01 7.56 × 106 3.48 × 106 0.067
a

Immunized non-Mamu-A∗01 macaques with low, intermediate, or high viral burdens were grouped according to their set point viremia.

b

Geometric mean viral burdens are reported as SIV RNA copies/ml of plasma.