TABLE 2.
Acute-phase and set point viral burdens in immunized and control macaques
| Macaques | Acute-phase burdenb
|
Set point burdenb
|
||||
|---|---|---|---|---|---|---|
| Immunized | Control | P value | Immunized | Control | P value | |
| All immunized versus all control | 2.38 × 106 | 3.28 × 107 | <0.0001 | 5.56 × 105 | 1.65 × 106 | 0.21 |
| Non-Mamu-A∗01 only | ||||||
| Immunized versus control | 2.64 × 106 | 4.66 × 107 | 0.0001 | 8.76 × 105 | 3.48 × 106 | 0.18 |
| Immunized-low burdena versus control | 3.43 × 106 | 4.66 × 107 | <0.01 | 7.20 × 104 | 3.48 × 106 | <0.01 |
| Immunized-intermediate burdena versus control | 1.75 × 106 | 4.66 × 107 | <0.01 | 1.23 × 106 | 3.48 × 106 | <0.01 |
| Immunized-high burdena versus control | 3.06 × 106 | 4.66 × 107 | <0.01 | 7.56 × 106 | 3.48 × 106 | 0.067 |
Immunized non-Mamu-A∗01 macaques with low, intermediate, or high viral burdens were grouped according to their set point viremia.
Geometric mean viral burdens are reported as SIV RNA copies/ml of plasma.