TABLE 1.
Evaluation of NEVA HIV with HIV-1 mixed-titer panels from Boston Biomedica Inc.a
| Panel | NEVAb HIV | Titer byc:
|
Result by:
|
||||
|---|---|---|---|---|---|---|---|
| GenSys HIV-1/2 | Abbott HIV-1/2 | Organon Teknika HIV-1 | Abbott HIV | Waldheim IFA RL1d | Ortho WBe | ||
| PRB106-01 | POS | 1.3 | 7.5 | 3.9 | 1.1 | R | POS |
| PRB106-02 | NEG | 0.2 | 1.8 | 0.4 | 3.3 | NR | NEG |
| PRB106-03 | POS | 1.6 | 2.0 | 2.4 | 2.7 | R | POS |
| PRB106-04 | POS | 3.9 | 8.9 | 4.2 | 0.5 | R | POS |
| PRB106-05 | POS | 2.5 | 17.6 | 5.8 | 0.4 | R | POS |
| PRB106-06 | NEG | 0.1 | 0.1 | 0.4 | 0.4 | NR | NEG |
| PRB106-07 | POS | 3.1 | 7.9 | 3.4 | 0.4 | R | POS |
| PRB106-08 | NEG | 0.9 | 15.7 | 0.9 | 11.5 | NR | IND |
| PRB106-09 | POS | 2.5 | 16.6 | 6.1 | 1.5 | R | POS |
| PRB106-10 | POS | 1.8 | 12.7 | 1.3 | 6.9 | R | POS |
| PRB106-11 | POS | 0.5 | 6.8 | 1.3 | 1.0 | NR | POS |
| PRB106-12 | POS | 0.6 | 2.4 | 3.1 | 10.6 | R | POS |
| PRB106-13 | POS | 2.5 | 10.5 | 3.8 | 0.4 | R | POS |
| PRB106-14 | POS | 1.7 | 6.0 | 2.2 | 2.0 | R | POS |
| PRB106-15 | POS | 1.9 | 5.5 | 4.2 | 1.6 | R | POS |
| PRB203-01 | POS | 4.6 | >16.3 | 6.4 | 0.9 | R | POS |
| PRB203-02 | POS | 6.8 | >16.3 | 6.6 | 1.0 | R | POS |
| PRB203-03 | NEG | 0.1 | 0.4 | 0.5 | 0.3 | NR | NEG |
| PRB203-04 | NEG | 0.3 | 13.1 | 0.6 | 23.3 | NR | IND |
| PRB203-05 | POS | 5.6 | >16.3 | 6.6 | 0.7 | R | POS |
| PRB203-06 | POS | 4.1 | 15.3 | 6.3 | 0.4 | R | POS |
| PRB203-07 | POS | 1.0 | 4.6 | 1.4 | 0.5 | R | POS |
| PRB203-08 | POS | 8.6 | >16.3 | 6.8 | 0.3 | R | POS |
| PRB203-09 | POS | 4.3 | >16.3 | 5.7 | 0.4 | R | POS |
| PRB203-10 | POS | 2.8 | 12.1 | 5.1 | 0.5 | R | POS |
| PRB203-11 | POS | 1.8 | 7.4 | 2.4 | 0.4 | R | POS |
| PRB203-12 | POS | 8.2 | >16.3 | 6.7 | 0.4 | R | POS |
| PRB203-13 | POS | 6.7 | >16.3 | 6.7 | 2.1 | R | POS |
| PRB203-14 | POS | 0.2 | 6.4 | 0.5 | 2.9 | NR | NEG |
| PRB203-15 | POS | 7.3 | >16.3 | 6.7 | 1.0 | R | POS |
| PRB203-16 | POS | 5.3 | 15.2 | 5.7 | 0.4 | R | POS |
| PRB203-17 | POS | 8.5 | >16.3 | 6.5 | 0.4 | R | POS |
| PRB203-18 | POS | 3.2 | 8.1 | 5.1 | 0.3 | R | POS |
| PRB203-19 | POS | 6.6 | >16.3 | 6.6 | 0.5 | R | POS |
| PRB203-20 | NEG | 0.1 | 0.3 | 0.4 | 0.4 | NR | NEG |
| PRB203-21 | POS | 7.8 | >16.3 | 6.4 | 0.3 | R | POS |
| PRB203-22 | POS | 0.8 | >16.3 | 1.8 | 11.0 | R | POS |
| PRB203-23 | POS | 7.6 | >16.3 | 6.7 | 1.1 | R | POS |
| PRB203-24 | POS | 1.0 | 6.5 | 3.2 | 0.4 | NR | POS |
| PRB203-25 | POS | 5.5 | >16.3 | 6.4 | 0.4 | R | POS |
a
The results obtained by a few EIAs, Western blotting, IFA, and HIV antigen detection are provided by panel supplier.
b
The agglutination reaction was recorded as negative (no visible agglutination) and positive (any agglutination more than that for the control reagent spot). POS, positive; NEG, negative.
c
In EIAs, values 1.0 or greater are considered reactive.
d
R, reactive; NR, nonreactive.
e
WB, Western blotting assay; POS, positive; NEG, negative; IND, indeterminate.