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. 2003 Jul;41(7):2900–2907. doi: 10.1128/JCM.41.7.2900-2907.2003

FIG. 3.

FIG. 3.

Relative frequency of sequence base mismatches and distribution of flanking nucleotides in 46 cross-sectional samples. (A) Distribution of complete and partial base pair mismatches expressed as percentages of the total mismatches within the cohort (n = 440). Nucleotide base pair mismatches A-G, A-R, and G-R showed significantly higher prevalences in the 46 samples than other mismatches (P < 0.001). (B) Relative proportion of bases immediately preceding the mismatches in the 5′ direction compared to the overall proportion of these bases within the cohort. N, ambiguous nucleotides. P < 0.001 for A; P = 0.05 for C; P < 0.001 for G; P = 0.27 for T. (C) Proportion of bases preceding the mismatches in the 3′ direction compared to the overall proportion of these bases within the cohort. P = 0.01 for A; P = 0.02 for C; P = 0.04 for G; P = 0.002 for T.