TABLE 1.
Patient no. | Age | Gender | Specimen | Concomitant infections and organisms | Diagnosis | Underlying comorbidity | Antibiotic exposure | Patient status | Antifungal treatment |
---|---|---|---|---|---|---|---|---|---|
1 | 11 yr | M | Bronchoalveolar lavage | Alpha-hemolytic streptococci | Bronchiolitis obliterans, organizing pneumonia | Bronchiectasis | Ampicillin, azithromycin, cefotaxime, primethoprim-sulfamethoxazole | Inpatient | No |
2 | 15 yr | F | Tracheal aspirate | None | Acute respiratory failure | Down syndrome, CHFb | Cefotaxime, vancomycin, erythromycin | Inpatient | No |
3 | 17 yr | F | Sputum | Coagulase-negative, staphylococcus, bloodstream infection | Hypoxia, megacolon, necrotizing enterocolitis | Spina bifida, ventriculoatrial shunt | Trimethoprim-sulfamethoxazole, ciprofloxacin, gentamicin, oxacillin | Inpatient | No |
4 | 19 yr | F | Sputum | Nonmucoid Pseudomonas aeruginosa, mucoid P. aeruginosa, Aspergillus fumigatus | Pseudomonas pneumonia | Cystic fibrosis, allergic bronchopulmonary aspergillosis | Tobramycin, ceftazidime, meropenem, itraconazole | Inpatient | No |
5 | 16 yr | M | Sputum | None | Pulmonary fibrosis | HIV infection, chronic renal failure, cardiomyopathy | Ampicillin-sulbactam, metronidazole, gentamicin, azithromycin, ticarcillin-clavulanate | Inpatient | Yes (fluconazole) |
6 | 5 yr | M | Blood | Staphylococcus epidermidis | Port infection | Factor VIII, deficiency | Vancomycin, gentamicin, oxacillin, clindamycin | Inpatient | Yes (amphotericin B, fluconazole) |
7 | 2 wk | M | Tongue | None | Thrush | None | None | Outpatient | NAf |
8 | 14 yr | F | Vagina | None | Vaginitis | None | None | Outpatient | NA |
9 | 15 yr | F | Vagina | Staphylococcus aureus | Vaginitis | None | None | Outpatient | NA |
10 | 2 yr | F | Skin | None | Diaper rash | None | None | Outpatient | NA |
11 | 16 yr | M | Abscess | Abscess, Cx + normal skin flora | Renal perirenal abscess, inpatient rehabilitation | Status post gunshot wound, resection of left kidney, spleen, and pancreatic tail; open abdominal wound, colostomy | None | Inpatient | Yes (fluconazole) |
12 | 18 yr | F | Urine | Neisseria gonorrhoeae, Chlamydia trachomatis Trichomonas vaginalis | Gonococcal salpingitis | Asthma fibromyalgia | Gentamicin, clindamycin | Inpatient | Yes (fluconazole) |
13 | 19 yr | F | Urine | Escherichia coli, coagulase-negative staphylococci | Urinary tract infection | None | Trimethoprim-sulfamethoxazole | Outpatient, (ED)e | No |
14 | 14 yr | F | Urine | Enterococcus sp., Corynebacterium sp. | Nephrolithiasis | Arnold-Chiari malformation VPd shunt, neurogenic bladder | Gentamicin, ampicillin | Inpatient | Yes (amphotericin B) |
M, male; F, female.
CHF, congestive heart failure.
Cx+, culture positive.
VP, ventriculoperitoneal.
ED, emergency department.
NA, not available.