Figure 4.

Increased cell death in the fly retina induced by dp53. dp53 was overexpressed in the fly retina under the control of a photoreceptor-specific promoter (gmr) using the UAS/GAL4 binary expression system (B and D). gmr-GAL4/+ served as wild-type control (A and C). Note the reduced size and the roughness of the eye caused by the overexpression of dp53 (B). (C and D) Third instar eye imaginal discs were subjected to acridine orange staining. Note the increased amount of cell death in the discs from animals overexpressing dp53 (D, arrow).