Table 1.
Hemodynamics, LV size, transmitral and transaortic Doppler, and IMP at baseline and with chronic LV dysfunction
| Baseline | Chronic LVD | |
| LV End Diastolic Volume (cc) | 41 ± 5 | 54 ± 8*** |
| LV End Systolic Volume (cc) | 15 ± 4 | 31 ± 12*** |
| Stroke Volume (cc) | 26 ± 3 | 23 ± 9 |
| LV Ejection fraction (%) | 63 ± 9 | 42 ± 3*** |
| LV Mass (g) | 61 ± 10 | 85 ± 11*** |
| LVSP (mm Hg) | 109 ± 14 | 111 ± 12 |
| LVEDP (mm Hg) | 6.2 ± 2.3 | 11.8 ± 4.9** |
| Cardiac Output (l/min) | 3.1 ± 0.7 | 2.8 ± 0.4 |
| Peak +dP/dT (mm Hg/sec) | 1874 ± 244 | 1388 ± 206*** |
| Tau (msec) | 24 ± 6 | 39 ± 5*** |
| E/A | 2.1 ± 1.3 | 1.5 ± 0.4* |
| Heart rate (beats/min) | 78 ± 12 | 93 ± 18* |
| Deceleration Time (msec) | 217 ± 38 | 129 ± 36** |
| ICT index (msec) | 40 ± 22 | 58 ± 31* |
| IRT index (msec) | 46 ± 19 | 63 ± 29 |
| LV ejection time index (msec) | 226 ± 23 | 201 ± 24* |
| IMP | 0.38 ± 0.14 | 0.60 ± 0.19** |
Abbreviations: E/A = peak rapid filling velocity/peak atrial filling velocity; ICT = isovolumic contraction time; IRT = isovolumic relaxation time; IMP = Index of myocardial performance; LVSP = LV systolic pressure; LVD = LV dysfunction; LVEDP = LV end diastolic pressure.
Statistics:*p < 0.05, **p < 0.01, ***p < 0.001 vs Baseline;