Table 2.
Analysis of gene expression in the fundus of wild type and W/WV mice
| Gene Name | W/WV/wildtype ratio(a) | Accession No. | Subcellular location(b) | Cytoband(c) |
| EST | 2.5 | AA185701 | ||
| EST | 2.5 | AA166336 | ||
| EST | 2.4 | AA021806 | ||
| MCM7: DNA Replication Licensing Factor | 2.4 | Q61881 | nucleus | 7q21.3-q22.1 |
| p160 ROCK2: Rho-Associated Protein Kinase | 2.3 | U58513 | cytoskeleton | 2p24 |
| EST | 2.3 | W18585 | ||
| EST | 2.3 | AA403748 | ||
| BST1/BP3: ADP-Ribosyl Cyclase 2 Precursor | 2.0 | Q64277 | membrane | 4p15 |
| EST | 2.0 | AA024250 | ||
| RBP2: retinol binding protein 2, cellular | 2.0 | Q08652 | cytoplasm | 3q23 |
| EST | 2.0 | W46016 | ||
| BP1/6C3: Glutamyl Aminopeptitase | -2.1 | S30398 | membrane | 16 |
| EST | -2.2 | AI552444 | ||
| EST | -2.3 | AA108876 | ||
| EST | -2.4 | AA049294 | ||
| EST | -2.4 | AA254777 | ||
| RHAMM: Hyaluronan-Mediated Motility Receptor | -2.5 | AF031932 | membrane | 5q33.2-qter |
| EST | -2.5 | AA002293 | ||
| EST | -3.4 | AI595081 | ||
| CPO: Coproporphyrinogen Oxidase | -3.6 | D16333 | mitochondria | 3q12 |
| EST | -3.9 | AA000304 |
(a) Balanced differential expression for control wild type mice vs W/W V mutant mice. Values that were decreased or increased by > 2-fold or greater in both two independent experiments were considered significant and the mean values were calculated. All of the results were confirmed with semi-quantitative RT-PCR using fundic tissues from six wild type and six W/WV mutant mice. (b) Subcellular location determined by the SOURCE program http://source.stanford.edu. (c) Human chromosomal localization of the gene.