Figure 2.

The NPD Compartment Browser. The compartment browser (A) provides an overview of each of the principal sub-nuclear compartments. Upon selecting a compartment (i.e. PML) an overview page (B) is generated with an image of that compartment and a short abstract describing its structure, function and relevance to human disease. Links to external Internet resources are also provided. In addition, the NPD can be searched for proteins associated with a given domain (C) from the overview page (i.e. BLM, Bright and CBP are returned for PML bodies). Nucleus illustration reproduced by permission of Dr David L. Spector, Cold Spring Harbor Laboratory.