Table 1.
Transduction of human and hamster cells by retroviral vectors having different Env proteins (pseudotypes)
| Vector pseudotype | Vector transduction of:
|
|
|---|---|---|
| HT-1080 human cells | A23 hamster cells | |
| RD114 | + | − |
| Xenotropic | + | − |
| FeLV-C | + | − |
| 10A1 | + | + |
| VSV-G | + | + |
LAPSN or LNCG vectors with the indicated pseudotypes were added to HT-1080 human and A23 hamster cells. Cells were stained for alkaline phosphatase expression (LAPSN) or were examined for green fluorescent protein expression (LNCG) 2 days after vector exposure, and transduction is indicated as + (≥104 FFU/ml of vector preparation) or − (≤10 FFU/ml).