Table 2.
Fibroblasts
|
T cells
|
|||||
---|---|---|---|---|---|---|
p53+/+ (n = 35) | p53+/− (n = 18) | p53−/− (n = 19) | p53+/+ (n = 19) | p53+/− (n = 8) | p53−/− (n = 11) | |
A. Mitotic recombination | 88 | 42 | 93 | 57 | 65 | 63 |
B. Chromosome loss with or without reduplication | 0 | 0 | 7 | 0 | 0 | 2 |
C. Deletion/gene conversion | 0 | 5 | 6 | 1 | 1 | 11 |
Total no. clones | 88 | 47 | 106 | 58 | 66 | 76 |
Fraction (%) of B and C | 0 | 11 | 12 | 2 | 2 | 17 |
n, Number of mice.