Table 1.
Genes differentially expressed between natural killer T cell clones ME10 and GW4
| Functional category | Accession no. | Common name | Cluster (row, column) |
|---|---|---|---|
| Surface receptor | |||
| U38276 | Semaphorin III | (1,1) | |
| U82169 | Frizzled | (1,1) | |
| M32315 | TNF-R | (1,2) | |
| U03397 | 4-1BB | (1,2) | |
| S77812 | VEGF-R | (1,2) | |
| X01057 | IL-2Rα | (1,2) | |
| Y00285 | IGF-R II | (1,2) | |
| L08096 | CD27 | (1,2) | |
| Z30426 | CD69 | (1,2) | |
| U76764 | CD97 | (1,2) | |
| U60800 | CD100 | (1,2) | |
| M24283 | Rhinovirus-R | (1,2) | |
| U19906 | Arginine vasopressin-R | (1,2) | |
| Z48042 | p137 | (1,2) | |
| D79206 | Ryudocan | (1,3) | |
| HT3125 | CD44 | (1,3) | |
| L39064 | IL-9R | (2,1) | |
| X14046 | CD37 | (2,1) | |
| L31584 | EBI-1 | (2,1) | |
| X97267 | LPAP | (2,1) | |
| M33680 | TAPA-1 | (2,2) | |
| M63175 | AMFR | (2,2) | |
| U60975 | gp250 | (2,2) | |
| Z50022 | C21orf3 | (2,2) | |
| U90546 | Butyrophilin BT4 | (2,3) | |
| U90552 | Butyrophilin BT5 | (2,3) | |
| X96719 | AICL | (2,3) | |
| Cytoskeleton | |||
| U80184 | Flightless I homolog | (1,1) | |
| X00351 | β-Actin | (1,2) | |
| U20582 | Actin-like peptide | (1,2) | |
| X82207 | β-Centractin | (1,2) | |
| X98534 | VASP | (1,2) | |
| D83735 | Calponin | (2,1) | |
| J00314 | β-Tubulin | (2,3) | |
| M21812 | Myosin LC | (2,3) | |
| X98411 | Myosin-IE | (2,3) | |
| Kinase/phosphatase | |||
| X79510 | PTP D1 | (1,1) | |
| L10717 | ITK | (1,2) | |
| X60673 | AK3 | (1,2) | |
| X85545 | PKX-1 | (1,2) | |
| D13720 | LYK | (1,2) | |
| HT1153 | Nm23-H2S | (1,2) | |
| M30448 | CK II β | (1,2) | |
| M90299 | Glucokinase | (1,2) | |
| U08316 | ISPK-1 | (1,2) | |
| X80910 | PPP1CB | (1,2) | |
| X93920 | DUSP-6 | (1,2) | |
| U24152 | PAK-1 | (1,3) | |
| D11327 | PTPN7 | (1,3) | |
| U15932 | DUSP-5 | (1,3) | |
| L16862 | GRK-6 | (2,1) | |
| L27071 | TXK | (2,1) | |
| J03805 | PPP2CB | (2,2) | |
| HT3678 | CLK-1 | (2,3) | |
| U66464 | HPK-1 | (2,3) | |
| X62535 | DAG kinase | (2,3) | |
| M31724 | PTP-1B | (2,3) | |
| Cytokine | |||
| U89922 | LT-β | (1,1) | |
| J00219 | IFN-γ | (1,2) | |
| V00536 | IFN-γ | (1,2) | |
| M13207 | GM-CSF | (1,2) | |
| M16441 | TNF-α | (1,2) | |
| X02910 | TNF-α | (1,2) | |
| X04688 | IL-5 | (1,2) | |
| U31120 | IL-13 | (1,2) | |
| M37435 | M-CSF | (1,2) | |
| U02020 | PBEF | (1,2) | |
| U37518 | TRAIL | (1,2) | |
| U46461 | Dishevelled homolog | (1,2) | |
| M90391 | IL-16 | (2,3) | |
| Nuclear protein | |||
| U73477 | Nuclear pp32 | (1,1) | |
| U62962 | Int-6 | (1,2) | |
| L25931 | Lamin B receptor | (1,3) | |
| M17733 | Thymosin-β4 | (2,3) | |
| Transcription factor | |||
| M69043 | IκBα | (1,2) | |
| X58072 | GATA-3 | (1,2) | |
| U43185 | STAT-5A | (1,2) | |
| X51345 | Jun-B | (1,2) | |
| X56681 | Jun-D | (1,2) | |
| U15460 | B-ATF | (1,2) | |
| HT4899 | C-myc | (1,2) | |
| L00058 | C-myc | (1,2) | |
| M13929 | C-myc | (1,2) | |
| U26173 | NF-IL3A | (1,2) | |
| M97796 | Id-2 | (1,2) | |
| M96843 | Id-2B | (1,2) | |
| D14826 | CREM | (1,2) | |
| S68271 | CREM | (1,2) | |
| J03827 | Y box BP | (1,2) | |
| U09412 | ZNF134 | (1,2) | |
| U13044 | NRF-2α | (1,2) | |
| U22431 | HIF-1α | (1,2) | |
| X78925 | HZF-2 | (1,2) | |
| Z47727 | RNA POL2K | (1,2) | |
| J04076 | EGR-2 | (1,3) | |
| D61380 | DJ-1 | (1,3) | |
| HT4567 | PC4 | (1,3) | |
| HT4921 | BTF-3 homolog | (2,1) | |
| L41067 | NFAT-4C | (2,3) | |
| L78440 | STAT-4 | (2,3) | |
| M82882 | ELF-1 | (2,3) | |
| M83667 | NF-IL6 | (2,3) | |
| Signal transduction | |||
| HT5108 | TRAP-3 | (1,1) | |
| X80200 | MLN62 | (1,1) | |
| U20158 | SLP-76 | (1,2) | |
| U26710 | Cbl-b | (1,2) | |
| D78132 | RHEB | (1,2) | |
| M63573 | SCYLP | (1,2) | |
| M75099 | FK506 BP | (1,2) | |
| Z35227 | TTF | (1,2) | |
| U19261 | EBV-independent | (1,3) | |
| M28209 | RAB-1 | (2,2) | |
| D78577 | 14-3-3-Eta | (2,3) | |
| X89399 | Ins(1345)P4 BP | (2,3) | |
| RNA Metabolism | |||
| D38251 | RNP B5 | (1,1) | |
| U90547 | RNP homolog | (1,1) | |
| X17567 | RNP B | (1,2) | |
| M29064 | RNP B1 | (1,2) | |
| HT110 | RNP A/B | (1,2) | |
| Z23064 | RNP G | (1,2) | |
| HT3238 | RNP K | (1,2) | |
| X52979 | RNP SmB | (1,2) | |
| U15009 | RNP SmD3 | (1,2) | |
| X85372 | RNP Sm F | (1,2) | |
| U30827 | SF SRp40 | (1,2) | |
| X70944 | SF (PTP-associated) | (1,2) | |
| M60858 | Nucleolin | (1,2) | |
| U10323 | NF45 | (1,2) | |
| U38846 | Stimulator of TAR | (1,2) | |
| X59417 | PROS-27 | (1,2) | |
| X59892 | IFN-independent γ2 | (1,2) | |
| X66899 | EWS | (1,2) | |
| X71428 | fus | (1,2) | |
| X72727 | Tunp | (1,2) | |
| X75755 | PR264 | (1,2) | |
| Z24724 | Poly A site | (1,2) | |
| L28010 | RNP F | (1,3) | |
| HT4788 | RNP I | (1,3) | |
| L03532 | M4 | (1,3) | |
| U69546 | RNA BP | (2,3) | |
| Apoptosis | |||
| Z23115 | Bcl-XL | (1,2) | |
| U45878 | IAP-1 | (1,2) | |
| U11821 | Fas ligand | (1,2) | |
| S81914 | IEX-1 | (1,2) | |
| U37546 | MIHC | (1,2) | |
| Chemokine | |||
| M23178 | MIP-1α | (1,2) | |
| J04130 | MIP-1β | (1,2) | |
| M69203 | MCP-1 | (1,2) | |
| L19686 | MIF | (1,3) | |
| Protein metabolism | |||
| D28473 | ILE-tRNA synthase | (1,2) | |
| U09510 | GLY-tRNA synthase | (1,2) | |
| L25085 | Sec61-β | (1,2) | |
| X74801 | Chaperonin cctg | (1,2) | |
| X77584 | Thioredoxin | (1,2) | |
| Y00281 | Ribophorin I | (1,2) | |
| Y10807 | ARG-methyltransferase | (1,3) | |
| D13748 | EIF-4AI | (1,3) | |
| X55733 | EIF-4B | (2,1) | |
| X76648 | Glutaredoxin | (2,3) | |
Genes populating the six expression clusters for the 11 gene functional categories shown in Fig. 2 are listed. Each gene is identified by GenBank accession no. [or The Institute for Genomic Research (TIGR) identifier for HT designations], followed by a common name and the specific cluster into which it fell (row, column).