Fig. 6. GST–Cdc42 or GST–Rac induced actin polymerization in WAVE2-deficient cell extracts. Kinetics of actin polymerization in the absence (blue) or presence of GTPγS-charged GST-Rac (green) or GTPγS-charged GST–Cdc42 (red). (A) Het (WAVE2+/neo); (B) KO (WAVE2neo/neo); (C) Rescue (WAVE2neo/neo+RVWAVE2).