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Restored 3-83 Id expression and B cell maturation in bone marrows of 3-83KIH mice compared with 3-83KI mice. (A) (Left) 3-83 Id/IgM double staining of bone marrow cells. (Right) Id levels on B220-gated bone marrow cells. (B) Enhanced development of sIgM+ cells and reduced pre-B population in 3-83KIH, compared with 3-83KI, bone marrows. (Left) B220/IgM double immunofluorescence. (Right) Pre-B cells enumerated as B220+/IgM−/CD43low cells.
