TABLE 3.
Serological results over time from patient 3a
| Time of serum sample | RF | Titer obtained with indicated test
|
CIEP result (no. of bands/titer) | Lateral flowc
|
|||||
|---|---|---|---|---|---|---|---|---|---|
| RB | SATb
|
Coombs IgG
|
|||||||
| pH 7.2 | pH 5.0 | pH 7.2 | pH 5.0 | IgM | IgG | ||||
| 27 May 1995 | ND | Neg | ND | ND | ND | ND | ND | ND | ND |
| 26 June 1995 | ND | 2 | 80 | ND | 640 | ND | ND | ND | ND |
| Specific antibiotic therapy (45 days) | |||||||||
| 3 mo | Neg | 16 | 160 | 320 | 2,560 | 2,560 | 2/8 | Neg | 3+-4+ |
| 6 mo | Neg | 16 | 80 | 160 | 2,560 | 2,560 | 2/4 | Neg | 2+ |
| 1 yr | Neg | 8 | 80 | 160 | 1,280 | 1,280 | 2/2 | Neg | 2+ |
| 2 yr | Neg | 4 | 20 | 80 | 1,280 | 1,280 | 2/2 | Neg | 1+ |
| 4 yr | Neg | 2 | 40 | 80 | 5,120 | 5,120 | 2/4 | Neg | 3+-4+ |
| 6 yr | Neg | Neg | 20 | 40 | 2,560 | 5,120 | 2/2 | Neg | 2+ |
| 8 yr | Neg | Neg | 20 | 40 | 2,560 | 2,560 | 2/2 | Neg | 1+-2+ |
| February 2004 (clinical relapse; antibiotic therapy, 6 mo) | |||||||||
| April 2004 (therapy, 2 mo) | Neg | Neg | 20 | 40 | 2,560 | 1,280 | 2/4 | Neg | 1+-2+ |
| July 2004 (liver resection) | |||||||||
| November 2004 | Neg | Neg | 20 | 40 | 1,280 | 1,280 | 2/4 | Neg | 1+-2+ |
Abbreviations: Neg, negative; ND, not done.
The SAT at pH 7.2 was done with milk ring test antigen (PBS); the SAT at pH 5.0 was done with Brucellacapt antigen (Vircell).
1+, weak staining; 2+, moderate staining; 3+, strong staining; 4+, very strong staining.